BE40644, a New Human Thioredoxin System Inhibitor Isolated from Actinoplanes sp. A40644.
نویسندگان
چکیده
منابع مشابه
Teicoplanin, a new antibiotic from Actinoplanes teichomyceticus nov. sp.
Teicoplanin, a new glycopeptide antibiotic belonging to the same family as vancomycin, inhibits cell wall synthesis in Bacillus subtilis; the inhibition is accompanied by an intracellular accumulation of UDP-N-acetyl-muramyl-pentapeptide. A cell-free system from Bacillus stearothermophilus, capable of synthesizing peptidoglycan, is 50% inhibited by teicoplanin at 40 micrograms/ml and 100% inhib...
متن کاملA new antimicrobial antibiotic from Actinoplanes capillaceus sp. K95-5561T.
deposited at Japan Collection of Microorganisms and the Institute for Fermentation, Osaka under accession number 10268T and 16408T, respectively. Detailed taxonomic study of the strain K95-55611 will be reported elsewhere3). A stock culture of the producing organism was inoculated into two 500-ml Erlenmeyer flasks containing 100ml of culturing medium. The flasks were incubated at 27°C for 72 ho...
متن کاملThe Human Thioredoxin System: Modifications and Clinical Applications
The thioredoxin system, comprising thioredoxin (Trx), thioredoxin reductase (TrxR) and NADPH, is one of the major cellular antioxidant systems, implicated in a large and growing number of biological functions. Trx acts as an oxidoreductase via a highly conserved dithiol/disulfide motif located in the active site ( Trp-Cys-Gly-Pro- Cys-Lys-). Different factors are involved in the regulation of T...
متن کاملDissipation of butachlor by a new strain of Pseudomonas sp. isolated from paddy soils
Butachlor (BUT) is a chloroacetanilide herbicide widely applied to rice paddies to control annual grass and broad-leaf weeds. A BUT-degrading bacterial strain (PK) was isolated from paddy soils. Biochemical and 16S rRNA sequencing characteristics confirmed the strain as Pseudomonas aeruginosa (99% resemblance). The isolate dissipated BUT (100 μg/mL) in an M9 liquid medium with a rate of 0.5 ± 0...
متن کاملDissipation of butachlor by a new strain of Pseudomonas sp. isolated from paddy soils
Butachlor (BUT) is a chloroacetanilide herbicide widely applied to rice paddies to control annual grass and broad-leaf weeds. A BUT-degrading bacterial strain (PK) was isolated from paddy soils. Biochemical and 16S rRNA sequencing characteristics confirmed the strain as Pseudomonas aeruginosa (99% resemblance). The isolate dissipated BUT (100 μg/mL) in an M9 liquid medium with a rate of 0.5 ± 0...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 1996
ISSN: 0021-8820,1881-1469
DOI: 10.7164/antibiotics.49.314